English: These considerations make it clear that it is impossible to have opinion and knowledge at the same time about the same object; otherwise one would apprehend that the same thing both could and could not be otherwise. (Loeb#391, p. 171)
Greek: Φανερὸν δ' ἐκ τούτων ὅτι οὐδὲ δοξάζειν ἅμα τὸ αὐτὸ καὶ ἐπίστασθαι ἐνδέχεται.ἅμα γὰρ ἂν ἔχοι ὑπόληψιν τοῦ ἄλλως ἔχειν καὶ μὴ ἄλλως τὸ αὐτό· Aristotle: Posterior Analytics [89a]
One destroys an opinion posing as knowledge by pointing out reality, invalid logic, assumptions, etc. If a model explains some, but not all, phenomena, one cannot discredit the model by pointing out what it does not explain. One really needs to come up with a better model. Example:
Older model: Newtonian physics (still valid in many respects)
Newer model: quantum and/or relativistic physics
Is a model an opinion? Is quantum mechanics an opinion?