Matthew 19:4 And he answered and said unto them, Have ye not read, that he which made them at the beginning made them male and female, [kjv]
ο δε αποκριθεις ειπεν ουκ ανεγνωτε οτι ο κτισας απ αρχης αρσεν και θηλυ εποιησεν αυτους [gnt]
Some in the culture have trouble determining the difference between
"male" and
"female".
In the beginning, the gene pool was not contaminated. Mutations after that could, in certain cases, muddy the waters. Note that in order to answer a question, Jesus (and others) must "
judge" since that Greek word is the root word of the word for "
answer".